*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG3100500
CHEMICAL NAME           : Benzoic acid,
                          3-(aminosulfonyl)-4-benzyl-5-(butylamino)-
CAS REGISTRY NUMBER     : 36148-38-6
BEILSTEIN REFERENCE NO. : 2783522
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H22-N2-O4-S
MOLECULAR WEIGHT        : 362.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(Aminosulfonyl)-4-benzyl-5-(butylamino)-benzoic acid
   * 4-Benzyl-3-n-butylamino-5-sulfamylbenzoic acid
   * Besunide
   * pINN
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,1170,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 186 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,1170,1973
 
                            *** END OF RECORD ***