*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG5015000
CHEMICAL NAME           : Benzoic acid, 4-chloro-,
                          3-ethyl-7-methyl-3,7-diazabicyclo(3.3.1)non-9-yl
                          ester, monohydrochloride
CAS REGISTRY NUMBER     : 89194-77-4
LAST UPDATED            : 199510
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C17-H23-Cl-N2-O2.Cl-H
MOLECULAR WEIGHT        : 359.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bisaramil
   * 4-Chlorobenzoic acid 3-ethyl-7-methyl-3,7-diazabicyclo(3.3.1)non-9-yl  
   ester hydrochloride
   *   3-Ethyl-7-methyl-9-alpha-(4'-chlorobenzoyloxy)-3,7-diazabicyclo(3.3.1)no
     name hydrochloride
   * alpha-Yutac
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 383 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,837,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 17600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,837,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 378 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,837,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,837,1985
 
                            *** END OF RECORD ***