*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF6492187
CHEMICAL NAME           : 2-Benzofurancarboxylic acid,
                          2,3-dihydro-6,7-dichloro-5-((dimethylamino)sulfonyl)-
CAS REGISTRY NUMBER     : 103968-87-2
LAST UPDATED            : 198812
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H11-Cl2-N-O5-S
MOLECULAR WEIGHT        : 340.19
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2,3-Dihydro-6,7-dichloro-5-((dimethylamino)sulfonyl)-2-benzofurancarboxy
     lic acid
   * S-8666
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2069 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,257,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 807 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,257,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 939 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,257,1988
 
                            *** END OF RECORD ***