*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG2278000
CHEMICAL NAME           : Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester,
                          monohydrochloride, mixt. with
                          3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
CAS REGISTRY NUMBER     : 8013-38-5
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H20-N2-O2.C8-H10-N4-O2.Cl-H
MOLECULAR WEIGHT        : 467.03
SYNONYMS/TRADE NAMES :
   * Cofocain
   * Impletol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 1,28,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4100 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,137,1959
 
                            *** END OF RECORD ***