*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF9486500
CHEMICAL NAME           : Benzo(a)heptalen-9(5H)-one,
                          6,7-dihydro-1,2,3-trimethoxy-10-(methylthio)-7-((2,3,
                          4,6-tetra- O-acetyl-beta-D-glucopyranosyl)amino)-,
                          (S)-
CAS REGISTRY NUMBER     : 66568-83-0
BEILSTEIN REFERENCE NO. : 5233750
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C34-H41-N-O13-S
MOLECULAR WEIGHT        : 703.82
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 NS1 JM- BT6OTJ COV1 DOV1
                          EOV1 F1OV1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Colchicine,  
   N-deacetyl-10-demethoxy-N-(tetra-O-acetyl-beta-D-glucopyranosyl)-10-(met  
   hylthio)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 109 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,636,1981
 
                            *** END OF RECORD ***