*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DF7875000
CHEMICAL NAME : 2(3H)-Benzofuranone,
3-(beta-diethylaminoethyl)-3-phenyl-
CAS REGISTRY NUMBER : 76-65-3
BEILSTEIN REFERENCE NO. : 0287893
REFERENCE : 4-18-00-07995 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 1
MOLECULAR FORMULA : C20-H23-N-O2
MOLECULAR WEIGHT : 309.44
WISWESSER LINE NOTATION : T56 BOV DHJ D2N2&2 DR
COMPOUND DESCRIPTOR : Human
SYNONYMS/TRADE NAMES :
* Amethone
* Amocaine
* Amolanone
* AP 43
* Butyric acid, 4-(diethylamino)-2-(o-hydroxyphenyl)-2-phenyl-,
gamma-lactone
* 3-(beta-Diethylaminoethyl)-3-phenyl-2-benzofuranone
* 3-(beta-Diethylaminoethyl)-3-phenyl-2-(3H)-benzofuranone
* 3-(2-(Diethylamino)ethyl)-3-phenyl-2(3H)-benzofuranone
* 3-(2-(Diethylamino)ethyl)-2-oxo-3-phenyl-2,3-dihydrobenzofuran
* gamma-Diethylamino-alpha-(o-hydroxyphenyl)-alpha-phenylbutyric acid
lactone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Human
DOSE/DURATION : 1400 ug/kg
TOXIC EFFECTS :
Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
spasmolytic)
Behavioral - hallucinations, distorted perceptions
Gastrointestinal - other changes
REFERENCE :
JOURAA Journal of Urology. (Williams & Wilkins Co., 428 E. Preston St.,
Baltimore, MD 21202) V.1- 1917- Volume(issue)/page/year: 54,75,1945
*** END OF RECORD ***