*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF6845120
CHEMICAL NAME           : 5-Benzofuranmethanol,
                          4,7-dimethoxy-alpha-(2-(4-hydroxyphenyl)ethyl)-6-
                          (2-(1-piperidinyl)ethoxy)-
CAS REGISTRY NUMBER     : 40680-87-3
BEILSTEIN REFERENCE NO. : 1276232
REFERENCE               : 5-20-02-00137 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H33-N-O6
MOLECULAR WEIGHT        : 455.60
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Piprofurol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 8,125,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 9,85,1974
 
                            *** END OF RECORD ***