*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF6423922
CHEMICAL NAME           : 4-Benzofuranacetamide,
                          N-methyl-N-(7-(1-pyrrolidinyl)-1-oxospiro(4.5)dec-8-y
                          l)-, monohydrochloride,
                          (5R-(5-alpha,7-alpha,8-beta))-
CAS REGISTRY NUMBER     : 124439-07-2
LAST UPDATED            : 199603
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H32-N2-O3.Cl-H
MOLECULAR WEIGHT        : 433.04
SYNONYMS/TRADE NAMES :
   * CI-977
   * Enadoline hydrochloride
   *   N-Methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxospiro(4.5)dec-8-yl)-4-ben
     zofuranacetamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1287 ng/kg/3W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Kidney, Ureter, Bladder - other changes in urine composition
   Nutritional and Gross Metabolic - other changes
REFERENCE :
   JCPCBR Journal of Clinical Pharmacology.  (Hall Assoc., PO Box 482,
   Stamford, CT 06904) V.13-    1973-  Volume(issue)/page/year: 34,1126,1994
 
                            *** END OF RECORD ***