*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF4935500
CHEMICAL NAME           : (1,3)-Benzodioxolo(5,6-c)phenanthridinium,
                          2,3-dimethoxy-12-methyl-, chloride
CAS REGISTRY NUMBER     : 13063-04-2
LAST UPDATED            : 199410
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H18-N-O4.Cl
MOLECULAR WEIGHT        : 383.85
WISWESSER LINE NOTATION : T G5 E6 B666 HO JO OK IHJ O1 SO1 TO1 &G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium  
   chloride
   * Nitidine chloride
   * NSC 146397
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 98980 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 40 ug/plate
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 66,1781,1977

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test

 
                            *** END OF RECORD ***