*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF4935150
CHEMICAL NAME           : 1,3-Benzodioxole,
                          5-((N-(2-(2-pyrimidinyl)-4-piperidyl)methylamino)meth
                          yl)-
CAS REGISTRY NUMBER     : 76167-85-6
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H22-N4-O2
MOLECULAR WEIGHT        : 326.44
WISWESSER LINE NOTATION : T56 BO DO CHJ G1N1&- DT6NTJ A- BT6N CNJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-((N-(2-(2-Pyrimidinyl)-4-piperidyl)methylamino)methyl)-1,3-benzodioxole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
   Vascular - relaxation (isolated tissues)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
   Vascular - relaxation (isolated tissues)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
                            *** END OF RECORD ***