*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2425000
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-1-(1-methyl-4-piperidinyl)-5-phenyl-
CAS REGISTRY NUMBER     : 93592-71-3
BEILSTEIN REFERENCE NO. : 5616950
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H23-N3-O
MOLECULAR WEIGHT        : 333.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,3-Dihydro-1-(1-methyl-4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-o
     ne
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 425 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 28,699,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4560684
 
                            *** END OF RECORD ***