*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2384333
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-7-n
                          itro-
CAS REGISTRY NUMBER     : 67739-71-3
LAST UPDATED            : 199606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H12-F-N3-O4
MOLECULAR WEIGHT        : 329.31
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,3-Dihydro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodi
     azepin-2-one
   * DP 327
   *   5-(2-Fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodi
     azepin-2-one
   * 3-Hydroxyflunitrazepam
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >8687 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0158267
 
                            *** END OF RECORD ***