*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2378000
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-7-chloro-5-phenyl-1-trimethylsilyl-
CAS REGISTRY NUMBER     : 55299-24-6
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H18-Cl-O-Si
MOLECULAR WEIGHT        : 313.90
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G-SI-1&1&1 KR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Chloro-1,3-dihydro-5-phenyl-1-trimethylsilyl-2H-1,4-benzodiazepin-2-one
   * ST 720
   * Trimethyl silyl-1 chloro-7 dihydro-1-3, phenyl-5 2H benzodiazepine 1-4  
   one-2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 36,621,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 36,621,1978
 
                            *** END OF RECORD ***