*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2374000
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-7-chloro-1-(2-morpholinoethyl)-5-phenyl-,
                          maleate (1:1)
CAS REGISTRY NUMBER     : 1061-21-8
LAST UPDATED            : 198606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H22-Cl-N3-O2.C4-H4-O4
MOLECULAR WEIGHT        : 499.99
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG KR& G2- AT6N DOTJ &QV1U1VQ -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7-Chloro-1,3-dihydro-1-(2-morpholinoethyl)-5-phenyl-2H-1,4-benzodiazepin
     -2-one maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 358 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - anticonvulsant
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,815,1965
 
                            *** END OF RECORD ***