*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2373700
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-7-chloro-1-(1-methyl-4-piperidinyl)-5-phe
                          nyl-, hydrochloride
LAST UPDATED            : 198511
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H22-Cl-N3-O.Cl-H
MOLECULAR WEIGHT        : 404.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,3-Dihydro-7-chloro-1-(1-methyl-4-piperidinyl)-5-phenyl-2H-1,4-benzodia
     zepin-2-one HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 548 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 28,699,1985
 
                            *** END OF RECORD ***