*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2373000
CHEMICAL NAME           : 2,3-(4H)-Benzodiazepin-4-one,
                          3,5-dihydro-8-chloro-3-methyl-1-phenyl-
CAS REGISTRY NUMBER     : 37388-25-3
BEILSTEIN REFERENCE NO. : 0888010
REFERENCE               : 5-24-04-00360 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H13-Cl-N2-O
MOLECULAR WEIGHT        : 284.76
WISWESSER LINE NOTATION : T67 HNNV KHJ DG GR& I1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3-(4H)-Benzodiazepin-4-one, 8-chloro-3,5-dihydro-3-methyl-1-phenyl-
   * 8-Chloro-3,5-dihydro-3-methyl-1-phenyl-2,3-(4H)-benzodiazepin-4-one
   * Isodiazepam
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 11,83,1976
 
                            *** END OF RECORD ***