*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2370300
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-m
                          ethyl-
CAS REGISTRY NUMBER     : 52391-89-6
BEILSTEIN REFERENCE NO. : 0688457
REFERENCE               : 5-25-02-00247 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H12-Cl-F-N2-O2
MOLECULAR WEIGHT        : 318.75
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G1 IQ KR BF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7-Chloro-1,3-dihydro-1-methyl-3-hydroxy-5-(2-fluorophenyl)-2H-1,4-benzod
     iazepin-2-one
   * Sas-646
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHMGBN Pharmacology: International Journal of Experimental and Clinical
   Pharmacology.  (S. Karger AG, Postfach CH-4009 Basel, Switzerland)  V.1-
   1968-  Volume(issue)/page/year: 12,74,1974
 
                            *** END OF RECORD ***