*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2368160
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          1,3-dihydro-7-chloro-1-(3-(diethylamino)propyl)-5-phe
                          nyl-, dihydrochloride
CAS REGISTRY NUMBER     : 1248-22-2
LAST UPDATED            : 198203
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H26-Cl-N3-O.2Cl-H
MOLECULAR WEIGHT        : 456.88
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G3N2&2 KR &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7-Chloro-1-(3-(diethylamino)propyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodia
     zepin-2-one 2HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 205 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - anticonvulsant
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,815,1965
 
                            *** END OF RECORD ***