*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE9735000
CHEMICAL NAME           : 3H-1,4-Benzodiazepin-3-ol,
                          7-chloro-2-(dimethylamino)-5-phenyl-
CAS REGISTRY NUMBER     : 76458-47-4
BEILSTEIN REFERENCE NO. : 4514158
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H16-Cl-N3-O
MOLECULAR WEIGHT        : 313.81
WISWESSER LINE NOTATION : T67 GN JN HHJ CG HN1&1 IQ KR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Chloro-2-(dimethylamino)-5-phenyl-3H-1,4-benzodiazepin-3-ol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 37,343,1982
 
                            *** END OF RECORD ***