*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE9640000
CHEMICAL NAME           : 1H-1,4-Benzodiazepine-1-propanenitrile,
                          2,3-dihydro-7-chloro-5-(2-fluorophenyl)-2-oxo-
CAS REGISTRY NUMBER     : 75696-02-5
BEILSTEIN REFERENCE NO. : 5359831
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H13-Cl-F-N3-O2
MOLECULAR WEIGHT        : 357.79
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G2CN IQ KR BF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cinolazepam
   * OX-373
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year: 7,98,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year: 7,98,1982
 
                            *** END OF RECORD ***