*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE9497500
CHEMICAL NAME           : 1H-1,4-Benzodiazepine,
                          2,3-dihydro-7-chloro-5-(2-chlorophenyl)-1-(4,5-dihydr
                          o-2-oxazolyl)-
CAS REGISTRY NUMBER     : 76053-14-0
LAST UPDATED            : 199606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H15-Cl2-N3-O
MOLECULAR WEIGHT        : 360.26
SYNONYMS/TRADE NAMES :
   *   2,3-Dihydro-7-chloro-5-(2-chlorophenyl)-1-(4,5-dihydro-2-oxazolyl)-1H-1,
     4-benzodiazepine
   * SC 32855
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1400 mg/kg/2W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Related to Chronic Data - changes in testicular weight
REFERENCE :
   RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
   Pub. Ltd., P.O. Box 966, Westbury, NY 11590)  V.1-    1970-
   Volume(issue)/page/year: 37,317,1982
 
                            *** END OF RECORD ***