*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE8746400
CHEMICAL NAME           : 1H-1,5-Benzodiazepine-2-carbonitrile,
                          7,7'-carbonylbis(2,3,4,5-tetrahydro-4-phenyl-
CAS REGISTRY NUMBER     : 87896-40-0
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C33-H28-N6-O
MOLECULAR WEIGHT        : 524.67
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AN-17
   *   7,7'-Carbonylbis(2,3,4,5-tetrahydro-4-phenyl-1H-1,5-benzodiazepine-2-car
     bonitrile)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 35,89,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1583 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 35,89,1983
 
                            *** END OF RECORD ***