*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE8029000
CHEMICAL NAME           : 5H-Benzo(4,5)cyclohepta(1,2-b)pyridin-5-ol,
                          10,11-dihydro-5-ethynyl-, hydrochloride
LAST UPDATED            : 198511
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H13-N-O.Cl-H
MOLECULAR WEIGHT        : 271.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10,11-Dihydro-5-ethynyl-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-ol  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,1415,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,1415,1971
 
                            *** END OF RECORD ***