*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE4924600
CHEMICAL NAME           : 1,2-Benzisoxazole,
                          6-chloro-3-(1H-imidazol-1-ylmethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 121929-34-8
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H8-Cl-N3-O.Cl-H
MOLECULAR WEIGHT        : 270.13
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Chloro-3-(1H-imidazol-1-ylmethyl)-1,2-benzisoxazole monohydrochloride
   * 3-Imidazol-1-il-metil-6-cloro-1,2-benzisossazolo cloridato
   * P-1368
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   128,177,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   128,177,1989
 
                            *** END OF RECORD ***