*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE4610000
CHEMICAL NAME           : 1,2-Benzisothiazolin-3-one, 2-(2-oxo-3-piperidyl)-,
                          1,1-dioxide
CAS REGISTRY NUMBER     : 49785-74-2
LAST UPDATED            : 199503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H12-N2-O4-S
MOLECULAR WEIGHT        : 280.32
WISWESSER LINE NOTATION : T56 BSWNVJ C- CT6MVTJ
SYNONYMS/TRADE NAMES :
   * CG 3033
   * 3-(2,3-Dihydro-1,1-dioxido-3-oxo-1,2-benzisothiazol-2-yl)-2-oxopiperidine
   * EM 87
   * 2-(2-Oxo-3-piperidyl)-1,2-benzisothiazolin-3-one 1,1-dioxide
   * Supidimide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,941,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3250 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,941,1981
 
                            *** END OF RECORD ***