*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD8070000
CHEMICAL NAME           : Benzimidazole,
                          1-(2-diethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitro-,
                          hydrochloride
CAS REGISTRY NUMBER     : 2053-25-0
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H28-N4-O3.Cl-H
MOLECULAR WEIGHT        : 433.00
WISWESSER LINE NOTATION : T56 BN DNJ B2N2&2 C1R DO2& GNW &GH
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * C 20684
   * 1-(2-Diethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole  
   hydrochloride
   * Etonitazene hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 126 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,889,1968
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6700 ng/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - other effects on male
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 198,340,1976
 
                            *** END OF RECORD ***