*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DD2810000
CHEMICAL NAME : Benzilic acid, 3-(diethylamino)propyl ester,
hydrochloride
CAS REGISTRY NUMBER : 55066-59-6
LAST UPDATED : 199109
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C21-H27-N-O3.Cl-H
MOLECULAR WEIGHT : 377.95
WISWESSER LINE NOTATION : QXR&R&VO3N2&2 &GH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Benzilate du diethylamino-propanolchlorhydrate
* 3-(Diethylamino)propyl benzilate hydrochloride
* Propanol, 3-(diethylamino)-, benzilate, hydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 48 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 9,404,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 19 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 9,404,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intradermal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 59,149,1938
*** END OF RECORD ***