*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DC4650000
CHEMICAL NAME           : 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride
CAS REGISTRY NUMBER     : 28094-15-7
LAST UPDATED            : 199609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H11-N-O3.Cl-H
MOLECULAR WEIGHT        : 205.66
WISWESSER LINE NOTATION : Z2R BQ CQ DQ &GH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 5-(2-Aminoethyl)-1,2,4-benzenetriol hydrochloride
   * 6-Hydroxydopamine chloride
   * 6-Hydroxydopamine hydrochloride
   * 2,4,5-Trihydroxyphenethylamine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
   Pub. Ltd., P.O. Box 966, Westbury, NY 11590)  V.1-    1970-
   Volume(issue)/page/year: 17,411,1977
 
                            *** END OF RECORD ***