*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB6831000
CHEMICAL NAME           : Benzenesulfonic acid,
                          2,2'-(1,2-ethanediyl)bis(5-amino-, disodium salt
CAS REGISTRY NUMBER     : 7336-20-1
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C14-H12-N2-O6-S2.2Na
MOLECULAR WEIGHT        : 414.38
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Amsonic acid disodium salt
   * p,p'-Diaminostilbene-o,o'-disulfonic acid disodium salt
   * Diaminostilbene disulphonate disodium salt
   * 2,2'-Disulfo-4,4'-stilbenediamine disodium salt
   * 2,3'-(1,2-Ethenediyl)bis(5-aminobenzenesulfonic acid) disodium salt
   * Flavonic acid disodium salt
   * 2,2'-Stilbenedisulfonic acid, 4,4'-diamino-, disodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 gm/kg/14D-C
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-412,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 546 gm/kg/13W-C
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Biochemical - Metabolism (Intermediary) - other proteins
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-412,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 168 gm/kg/14D-C
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-412,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1092 gm/kg/13W-C
TOXIC EFFECTS :
   Behavioral - tremor
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-412,1992

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2053
       No. of Facilities: 3525 (estimated)
       No. of Industries: 7
       No. of Occupations: 13
       No. of Employees: 15522 (estimated)
       No. of Female Employees: 8206 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NTP Carcinogenesis Studies (feed);no evidence:rat,mouse
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-412,92

 
                            *** END OF RECORD ***