*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB5042500
CHEMICAL NAME           : Benzenesulfonic acid,
                          2-anilino-5-(2,4-dinitroanilino)-, monosodium salt
CAS REGISTRY NUMBER     : 6373-74-6
OTHER CAS REGISTRY NOS. : 74968-36-8
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C18-H13-N4-O7-S.Na
MOLECULAR WEIGHT        : 452.40
WISWESSER LINE NOTATION : WSQR BMR& DMR BNW DNW &-NA-
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acid Fast Yellow AG
   * Acid Fast Yellow E5R
   * Acid Leather Light Brown G
   * Acid Orange No. 3
   * Acid Yellow E
   * Airedale Yellow E
   * Amido Yellow E
   * Amido Yellow EA
   * Amido Yellow EA-CF
   * 2-Anilino-5-(2,4-dinitroanilino)benzenesulfonic acid sodium salt
   * Anthralan Yellow RRT
   * Benzenesulfonic acid, 5-((2,4-dinitrophenyl)amino)-2-(phenylamino)-,  
   monosodium salt
   * C.I. 10385
   * C.I. Acid Orange 3
   * Coranil Brown H EPS
   * Derma FUR Yellow RT
   * Derma Yellow P
   * Dimacide Yellow N-5RL
   * 5-((2,4-Dinitrophenyl)amino)-2-(phenylamino)benzenesulfonic acid  
   monosodium salt
   * Duasyn Acid Yellow RRT
   * Elbenyl Orange A-3RD
   * Erio Fast Yellow AE
   * Erio Fast Yellow AEN
   * Erionyl Yellow E-aen
   * Erio Yellow AEN
   * Fast Light Yellow E
   * Fenalan Yellow E
   * Heliacid Light Yellow 4R
   * Intranyl Orange T-4R
   * Kiton Fast Yellow A
   * Lanaperl Yellow Brown GT
   * Light Fast Yellow ES
   * Lissamine Fast Yellow AE
   * Lissamine Fast Yellow AES
   * Lissamine Yellow AE
   * Multacid Yellow 3R
   * Multicuer Brown MPH
   * Nailamide Yellow Brown E-L
   * NCI-C54911
   * Nylocrom Yellow 3R
   * Nylomine Acid Yellow B-RD
   * Nylosan Yellow E-3R
   * Polan Yellow E-3R
   * Sellacid Yellow AEN
   * Sodium 4-(2,4-dinitroanilino)diphenylamine-2-sulfonate
   * Solanile Yellow E
   * Sulfacid Light Yellow 5RL
   * Superian Yellow R
   * Tectilon Orange 3GT
   * Tertracid Light Yellow 2R
   * Unitertracid Light Yellow RR
   * Vondacid Fast Yellow AE
   * Vondacid Light Yellow AE
   * Xylene Fast Yellow ES
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 97500 mg/kg/13W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
   Related to Chronic Data - death
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-335,1988
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 65 gm/kg/13W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-335,1988
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 386 gm/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-335,1988
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,121,1993

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,121,1993

   IARC Cancer Review:Group 3
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,121,1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X9543
       No. of Facilities: 2258 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 22238 (estimated)
       No. of Female Employees: 14728 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NTP Carcinogenesis Studies (gavage);clear evidence:rat
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-335,88

   NTP Carcinogenesis Studies (gavage);no evidence:mouse
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-335,88

 
                            *** END OF RECORD ***