*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA9500800
CHEMICAL NAME           : Benzenesulfonamide,
                          4-amino-N-(4,6-dimethoxy-2-pyrimidinyl)-, sodium salt
LAST UPDATED            : 199303
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H14-N4-O4-S.Na
MOLECULAR WEIGHT        : 333.35
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-N-(4,6-dimethoxy-2-pyrimidinyl)benzenesulfonamide sodium salt
   * Sale sodico della 2-p-aminobenzensulfonamido-4,6-dimetossi-pirimidina
   * Sodium sulphadimethoxypyrimidine
   * Sulfanilamide, N(sup 1)-(4,6-dimethoxy-2-pyrimidinyl)-, sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1788 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 2,149,1947
 
                            *** END OF RECORD ***