*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA8336000
CHEMICAL NAME           : Benzenepropanoic acid,
                          alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl
                          )-4-hydroxy-, monohydrochloride, (S-(R*,S*))-
CAS REGISTRY NUMBER     : 88465-81-0
LAST UPDATED            : 199304
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H24-N4-O4.Cl-H
MOLECULAR WEIGHT        : 372.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   alpha-(3-Amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-4-hydroxybenzenep
     ropanoic acid
   * 5-Amino-8-guanidino-2-(4-hydroxyphenylmethyl)-4-oxooctanoic acid  
   hydrochloride
   * Arphamenine B
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 36,1572,1983
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #96356
 
                            *** END OF RECORD ***