*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA8325700
CHEMICAL NAME           : Benzenepropanamide,
                          4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-beta-methyl-al
                          pha-oxo-
CAS REGISTRY NUMBER     : 67358-82-1
BEILSTEIN REFERENCE NO. : 1548094
REFERENCE               : 5-21-08-00031 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H16-N2-O3
MOLECULAR WEIGHT        : 308.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-beta-methyl-alpha-oxobenzenepropa
     namide
   * GP 650
   * 3-Methyl-3-(4-(1-oxo-2-isoindolinyl)phenyl)pyruvic acid amide
   * 2-Oxo-3-(4-(1-oxo-2-isoindolinyl)phenyl)butanamide
   * 2-Oxo-3-(4-(1-oxo-2-isoindolinyl)phenyl)buttersaeure-amid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,225,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2755345
 
                            *** END OF RECORD ***