*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA0460000
CHEMICAL NAME           : Benzeneethanol, 4-(bis(2-chloroethyl)amino)-, acetate
                          (ester)
CAS REGISTRY NUMBER     : 29427-51-8
LAST UPDATED            : 199412
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H19-Cl2-N-O2
MOLECULAR WEIGHT        : 304.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetic acid, (p-(bis(2-chloroethyl)amino)phenylethyl) ester
   * 4-(Bis(2-chloroethyl)amino)benzeneethanol acetate (ester)
   * NSC 116785
   * Phenester
   * Phenethyl alcohol, p-(bis(2-chloroethyl)amino)-, acetate (ester)
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg/5D-I
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Blood - methemoglobinemia-carboxyhemoglobin
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,841,1971
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 77 mg/kg/40D-I
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,841,1971
 
                            *** END OF RECORD ***