*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA0289990
CHEMICAL NAME           : Benzeneethanamine, N,N-dimethyl-alpha-phenyl-,
                          hydrochloride, (-)-
LAST UPDATED            : 199409
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C16-H19-N.Cl-H
MOLECULAR WEIGHT        : 261.82
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (-)-N,N-Dimethyl-alpha-phenylbenzeneethanamine hydrochloride
   * Ethylamine, N,N-dimethyl-1,2-diphenyl-, hydrochloride, (l)-
   * (-)-Lefetamina clorhidrato
   * (-)-Lefetamine hydrochloride
   * Phenethylamine, N,N-dimethyl-alpha-phenyl-, hydrochloride, (-)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLTEA4 Clinica Terapeutica (Rome).  (Societa Editrice Universo, Via G.B.
   Morgagni, 1, I-00161 Rome, Italy)  V.1-    1955-  Volume(issue)/page/year:
   102,25,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLTEA4 Clinica Terapeutica (Rome).  (Societa Editrice Universo, Via G.B.
   Morgagni, 1, I-00161 Rome, Italy)  V.1-    1955-  Volume(issue)/page/year:
   102,25,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLTEA4 Clinica Terapeutica (Rome).  (Societa Editrice Universo, Via G.B.
   Morgagni, 1, I-00161 Rome, Italy)  V.1-    1955-  Volume(issue)/page/year:
   102,25,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 128 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLTEA4 Clinica Terapeutica (Rome).  (Societa Editrice Universo, Via G.B.
   Morgagni, 1, I-00161 Rome, Italy)  V.1-    1955-  Volume(issue)/page/year:
   102,25,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,1953,1980
 
                            *** END OF RECORD ***