*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CZ8960000
CHEMICAL NAME           : 1,2-Benzenediol,
                          4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (R)-,
                          (R-(R*,R*))-2,3- dihydroxybutanedioate (1:1) (salt)
CAS REGISTRY NUMBER     : 54750-10-6
LAST UPDATED            : 198912
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H17-N-O3.C4-H6-O6
MOLECULAR WEIGHT        : 361.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Isolevin
   * Isolevine
   * (-)-Isoprenaline bitartrate
   * l-Isoprenaline bitartrate
   * (-)-Isoprenaline tartrate
   * Isopropylnoradrenaline bitartrate
   * (-)-Isoproterenol bitartrate
   * l-Isoproterenol bitartrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3768 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 21,1,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 849 mg/kg
TOXIC EFFECTS :
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 21,1,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 21,1,1953
 
                            *** END OF RECORD ***