*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CZ6457000
CHEMICAL NAME           : 1,3-Benzenedimethanol,
                          4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)met
                          hyl)-, (+-)-
CAS REGISTRY NUMBER     : 89365-50-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H37-N-O4
MOLECULAR WEIGHT        : 415.63
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (+-)-4-Hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benze
     nedimethanol
   * GR 33343X
   * Salmeterol
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5600 ug/kg/28D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - changes in spleen
   Immunological Including Allergic - decreased immune response
REFERENCE :
   IJIMDS International Journal of Immunopharmacology.  (Pergamon Press Inc.,
   Maxwell House, Fairview Park, Elmsford, NY 10523)  V.1-    1979-
   Volume(issue)/page/year: 18,523,1996
 
                            *** END OF RECORD ***