*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AE2250000
CHEMICAL NAME           : Acetanilide,
                          4-((p-(dimethylamino)phenyl)azo)-N-methyl-
CAS REGISTRY NUMBER     : 33804-48-7
BEILSTEIN REFERENCE NO. : 1843905
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C17-H20-N4-O
MOLECULAR WEIGHT        : 296.41
WISWESSER LINE NOTATION : 1VN1&R DNUNR DN1&1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acetamide, N-(4-((4-(dimethylamino)phenyl)azo)phenyl)-N-methyl-
   * N'-Acetyl-N'-methyl-4'-amino-N,N-dimethyl-4-aminoazobenzene
   * Azobenzene, 4-(N-acetyl-N-methyl)amino-4'-(N',N'-dimethylamino)-
   * N',N'-Dimethyl-4'-amino-N-acetyl-N-monomethyl-4-aminoazobenzene
   * 4-((p-(Dimethylamino)phenyl)azo)-N-methylacetanilide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   34,2274,1974
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1630 mg/kg/21W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   34,2274,1974
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 nmol/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,1654,1986
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,1654,1986
 
                            *** END OF RECORD ***