*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AC8660000
CHEMICAL NAME           : Acetamide,
                          N-(5,6,7,9-tetrahydro-10-(methylthio)-9-oxo-1,2,3-tri
                          methoxybenzo(a)heptal en-7- yl)-2,2,2-trifluoro-,
                          (S)-
CAS REGISTRY NUMBER     : 76129-16-3
BEILSTEIN REFERENCE NO. : 5318221
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H22-F3-N-O5-S
MOLECULAR WEIGHT        : 469.51
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 JMVXFFF NS1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Colchicine, 10-demethoxy-10-(methylthio)-17,17,17-trifluoro-
   * Colchicine, 10-thio-17,17,17-trifluoro-
   * N-(Trifluoroacetyl)deacetylthiocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1451 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,636,1981
 
                            *** END OF RECORD ***