*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AC8586000
CHEMICAL NAME           : Acetamide,
                          N-(5,6,7,9-tetrahydro-1,2-dimethoxy-3-hydroxy-10-(met
                          hylthio)-9-oxobenzo(a) heptalen-7-yl)-, (S)-
CAS REGISTRY NUMBER     : 87424-25-7
BEILSTEIN REFERENCE NO. : 3176383
REFERENCE               : 4-14-00-00956 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H23-N-O5-S
MOLECULAR WEIGHT        : 401.51
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Colchicine, O(sup 3)-demethyl-10-thio-
   * 3-Demethylthiocolchicine
   * O(sup 3)-Demethyl-10-thiocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 28,1204,1985
 
                            *** END OF RECORD ***