*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CY1678870
CHEMICAL NAME           : Benzeneacetic acid, alpha-methyl-3-phenoxy-, calcium
                          salt, (+-)-
CAS REGISTRY NUMBER     : 34597-40-5
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H26-O6.Ca
MOLECULAR WEIGHT        : 522.64
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Calcium fenoprofen
   * Fenoprofen calcium
   * (+-)-alpha-Methyl-3-phenoxybenzeneacetic acid calcium salt
   * Nalfon
   * dl-2-(3-Phenoxyphenyl)propionic acid calcium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 415 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
   Gastrointestinal - hypermotility, diarrhea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 14,4385,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 686 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
   Blood - changes in spleen
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 14,4385,1980
 
                            *** END OF RECORD ***