*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CY1480500
CHEMICAL NAME           : Benzeneacetamide,
                          alpha-((acetyloxy)methyl)-N-(2-pyridinylmethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 36256-92-5
LAST UPDATED            : 198503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H18-N2-O3.Cl-H
MOLECULAR WEIGHT        : 334.83
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-((Acetyloxy)methyl)-N-(2-pyridinylmethyl)benzeneacetamide  
   hydrochloride
   * PAT-2
   * 2-Pyridylmethylamide of acetyltropic acid hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1350 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   27,139,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 351 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   27,139,1975
 
                            *** END OF RECORD ***