*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CW1925000
CHEMICAL NAME           : Benz(a)anthracene-7,12-dimethanol
CAS REGISTRY NUMBER     : 2564-65-0
BEILSTEIN REFERENCE NO. : 1997775
REFERENCE               : 3-06-00-05845 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C20-H16-O2
MOLECULAR WEIGHT        : 288.36
WISWESSER LINE NOTATION : L D6 B666J C1Q J1Q
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 9:10-Bishydroxymethyl-1:2-benzanthracene
   * 7,12-Dihydroxymethylbenz(a)anthracene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2600 mg/kg/40W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   PRLBA4 Proceedings of the Royal Society of London, Series B: Biological
   Sciences.  (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 
     1905-  Volume(issue)/page/year: 129,439,1940
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 nmol/plate
REFERENCE :
   46OJAN "Chemical Analysis and Biological Fate: Polynuclear Aromatic
   Hydrocarbons, 5th International Symposium, 1980," Cooke, M., and A.J.
   Dennis, eds., Columbus, OH, Battelle Press, 1981  Volume(issue)/page/year:
   -,675,1981
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 gm/L/2H
REFERENCE :
   GENTAE Genetics.  (Genetics Business Office, POB 64025, Baltimore, MD 21264)
    V.1-    1916-  Volume(issue)/page/year: 39,141,1954

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: V79 cell culture-gene mutation
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat

 
                            *** END OF RECORD ***