*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CW1050000
CHEMICAL NAME           : Benz(a)anthracene, 7-cyano-
CAS REGISTRY NUMBER     : 7476-08-6
BEILSTEIN REFERENCE NO. : 3318100
REFERENCE               : 4-09-00-02746 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H11-N
MOLECULAR WEIGHT        : 253.31
WISWESSER LINE NOTATION : L D6 B666J JCN
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Benz(a)anthracene-7-carbonitrile
   * 7-Cyanobenz(a)anthracene
   * 10-Cyano-1,2-benzanthracene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1370 mg/kg/57W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   PRLBA4 Proceedings of the Royal Society of London, Series B: Biological
   Sciences.  (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 
     1905-  Volume(issue)/page/year: 131,170,1942
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2400 mg/kg/36W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - lymphoma, including Hodgkin's disease
   Tumorigenic - tumors at site of application
REFERENCE :
   PRLBA4 Proceedings of the Royal Society of London, Series B: Biological
   Sciences.  (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 
     1905-  Volume(issue)/page/year: 129,439,1940
 
                            *** END OF RECORD ***