*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CV6527000
CHEMICAL NAME           : Benzamidine, 4,4'-(pentamethylenedioxy)di-,
                          methanesulfonate
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H24-N4-O2.C-H4-O3-S
MOLECULAR WEIGHT        : 436.58
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * 4,4'-(Pentamethylenedioxy)dibenzamidine methanesulfonate
   * Pentamidine mesylate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 21 mg/kg/6D-I
TOXIC EFFECTS :
   Cardiac - pulse rate
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   294,1101,1987
 
                            *** END OF RECORD ***