*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CV2347360
CHEMICAL NAME           : Benzamide,
                          5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)
                          -1-hydroxyethyl)-2-hy droxy-, monohydrochloride
CAS REGISTRY NUMBER     : 70161-10-3
LAST UPDATED            : 199507
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H24-N2-O5.Cl-H
MOLECULAR WEIGHT        : 408.92
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   *   5-(2-((3-(1,3-Benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-
     hydroxybenzamide HCl
   * Medroxalol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 137 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Musculoskeletal - tumors
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 15,457,1987
 
                            *** END OF RECORD ***