*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CU4335000
CHEMICAL NAME           : Benz(c)acridine, 7,8,11-trimethyl-
CAS REGISTRY NUMBER     : 64038-40-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C20-H17-N
MOLECULAR WEIGHT        : 271.38
WISWESSER LINE NOTATION : T D6 B666 CNJ F1 H1 J1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1,4,10 Trimethyl,7:8 benzacridine
   * 5,6,9-Trimethyl-1:2-benzacridine
   * 7,8,11-Trimethylbenz(c)acridine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 270 mg/kg/25W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   ACRSAJ Advances in Cancer Research.  (Academic Press, Inc., 465 S. Lincoln
   Dr., Troy, MO 63379) V.1-    1953-  Volume(issue)/page/year: 4,315,1956
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   7,184,1950
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 280 mg/kg/23W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   7,184,1950
 
                            *** END OF RECORD ***