*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CU4100000
CHEMICAL NAME           : Benz(c)acridine, 7-methyl-9-phenyl-
CAS REGISTRY NUMBER     : 21075-41-2
BEILSTEIN REFERENCE NO. : 0260489
REFERENCE               : 4-20-00-04477 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H17-N
MOLECULAR WEIGHT        : 319.42
WISWESSER LINE NOTATION : T D6 B666 CNJ GR& J1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 5-Methyl-7-phenyl-1:2-benzacridine
   * 7-Methyl-9-phenylbenz(c)acridine
   * 3 Phenyl,10 methyl,7:8 benzacridine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 390 mg/kg/32W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   7,184,1950
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   7,184,1950
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg/34W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Lungs, Thorax, or Respiration - bronchiolar constriction
REFERENCE :
   ACRSAJ Advances in Cancer Research.  (Academic Press, Inc., 465 S. Lincoln
   Dr., Troy, MO 63379) V.1-    1953-  Volume(issue)/page/year: 4,315,1956
 
                            *** END OF RECORD ***