*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CQ6200000
CHEMICAL NAME           : Barbituric acid, 5-ethyl-5-(1-methylbutyl)-, sodium
                          salt, R(+)-
CAS REGISTRY NUMBER     : 21642-83-1
LAST UPDATED            : 198909
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H18-N2-O3.Na
MOLECULAR WEIGHT        : 249.30
WISWESSER LINE NOTATION : T6VMVNV FHJ FY3&1 F2 &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * R(+)-5-Ethyl-5-(1-methylbutyl)barbituric acid sodium salt
   * (+)-Pentobarbital
   * R(+)-Pentobarbital
   * R(+)-Pentobarbital sodium
   * 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-, monosodium  
   salt, (R)-
   * Sodium (R)(+)-pentobarbital
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 56,1772,1934
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 204 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - excitement
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   26,495,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 162 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - excitement
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   26,495,1973
 
                            *** END OF RECORD ***