*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CO1741000
CHEMICAL NAME           : 8-Azoniabicyclo(3.2.1)octane,
                          8-(2-((4-(aminosulfonyl)phenyl)amino)-2-oxoethyl)-3-h
                          ydroxy- 8-methyl-, chloride, endo-
CAS REGISTRY NUMBER     : 93614-59-6
LAST UPDATED            : 198809
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H24-N3-O4-S.Cl
MOLECULAR WEIGHT        : 389.94
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chlorek N-(4'-sulfamylofenyloamino-N'-acetylo)-tropiniowy
   * N-(4'-Sulfamoylphenylamine-N'-acetyl)tropinium chloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   HPBIA9 Herba Polonica.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)
   V.11-    1965-  Volume(issue)/page/year: 29,135,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   HPBIA9 Herba Polonica.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)
   V.11-    1965-  Volume(issue)/page/year: 29,135,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   HPBIA9 Herba Polonica.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)
   V.11-    1965-  Volume(issue)/page/year: 29,135,1983
 
                            *** END OF RECORD ***